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众所周知，医用手套对医护人员是重要的屏障保护。
有趣味的是，最新的一项研究表明，“抗菌手套”可显著降低“microbial passage ”，从而降低获得性感染的发生。
文章如下：Am J Infect Control. 2011 Mar;39(2):98-103.
Abstract
BACKGROUND: Surgical gloves provide a protective barrier for patients and members of the surgical team. Although glove integrity is important in an era of blood-borne pathogens, little data exist on bacterial passage after glove perforation. This study evaluated the impact of antimicrobial surgical gloves in reducing microbial passage after glove puncture in a model of wound contamination.
METHODS: Staphylococcus aureus (ATCC 6538) and Brevundimonas diminuta (DSM 1639) were used to prepare a standardized suspension for testing bacterial passage after glove puncture in volunteers wearing single-layer gloves (group A), double-layer gloves (group B), or antimicrobial trilayer gloves (group C). After exposure periods of 5, 10, 30 and 45 minutes, the outer test gloves were removed and microbial passage was measured on the inner surface of the base gloves. Multiple repetitions (5 or 6) were performed at each sampling time.
RESULTS: Microbial passage at 5-, 10-, 30-, and 45-minute exposures were analyzed both separately and combined (5 and 10 minutes and 30 and 45 minutes). No difference was observed in microbial passage between group A and group B at the 10-, 30-, and 45-minute exposures for S aureus, whereas a significant reduction in microbial passage was observed in group C compared with group A (P ≤ .05 to < .005) at the 5-, 30-, and 45-minute exposures for both S aureus and B diminuta. When timed groups were combined (5 and 10 minutes and 30 and 45 minutes), a significant reduction (P ≤ .01 to ≤ .005) in microbial passage of S aureus and B diminuta was observed in group C compared with both group A and group B.
CONCLUSION:These findings represent the first evidence that microbial passage across surgical gloves can be reduced significantly using an innovative antimicrobial glove technology.
这是个新的思路，但是还有一些潜在的问题：
1.手套上的消毒剂或者抑菌剂对机体的毒理学效应如何？
2.消毒剂或者抑菌剂的稳定性怎样？
3.由于本研究仅仅研究两种指示菌（Staphylococcus aureus and Brevundimonas diminuta ），可能还需要更多的证据支持其应用价值。
尽管如此，它确实给我们带来了新的思路，对“屏障预防”也是个重要的补充。
PS：文中的microbial passage 没有翻译，因为尽管能够了解他的意思，我也没有找到合适的词。希望有经验的站友帮我补充！
上一篇:含氯消毒剂的监测记录下一篇:求助进行生物监测时，生物指示菌片的温度必须和灭菌器的温度相同吗？
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发表于 2011-3-3 12:24:00
发表于 2011-3-3 12:24:01
